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Atg14 molecular weight: Beclin 1-associated autophagy-related key regulator

Rubicon, which localizes to the endosome and lysosome, inhibits Vps34 lipid kinase activity; knockdown of Rubicon enhances autophagy and endocytic trafficking 11,

Matthew Cox
Friday, October 9, 2020
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  • Basic sequence-derived length, molecular weight, isoelectric point and experimentally-determined median abundance, median absolute deviation protein information.

  • Complex I is involved in autophagy, whereas complex II is involved in vacuolar protein sorting.

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  • Encyclopedia of Proteome Dynamics More PRO i.

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Certificate of Origin. Citations Not applicable. Protein sequence database of the Protein Information Resource More Changing to another country might result in loss of shopping cart. This product is discontinued.

DisGeNET i. International Journal of Cell Biology, Reactome - a knowledgebase of biological pathways and processes More Angiotensin II suppresses autophagy and disrupts ultrastructural morphology and function of mitochondria in mouse skeletal muscle. Please consider upgrading your browser.

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KEGG i. Your basket is currently empty. RNAct i.

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  • Comparative Toxicogenomics Database More NONH for all modes of transport.

Physical form Solution in 0. Nonfat Dry Milk : Download protocol. Sun, Q. Filter: WB.

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Corvera, S. This antibody also cross-reacts with unidentified proteins of 32 kDa, 80 kDa and kDa. Inquiry Info. P With Exp. PIR i.

Protein interaction database and analysis system More MobiDB: a database of protein disorder and mobility annotations More Pfam i. Pore size 0.

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Treat cells by adding fresh media containing regulator for desired time. Weight Da Gene Information.

MINT i. Basic sequence-derived length, molecular atg14 molecular weight, isoelectric point and experimentally-determined median abundance, median absolute deviation protein information. VEuPathDB i. Summary Subunit of the phosphatidylinositol 3-kinase complex I involved in macroautophagy, cytoplasm-to-vacuole targeting CVT pathway, peroxisome degradation, piecemeal microautophagy of nucleus; also localizes to the pre-autophagosomal structure PAS View computational annotations Molecular Function Manually Curated enables molecular function unknown ND. Sun, Q. This is version of the entry and version 1 of the sequence. SGD has manually curated and high-throughput GO Annotations, both derived from the literature, as well as computational, or predicted, annotations.

You are using a version of browser that milecular not display all the features of this website. Any Customer's terms and conditions that are in addition to, or different from, those contained herein, unless separately accepted in writing by a legally authorized representative of CST, are rejected and are of no force or effect. Antibodies are purified by protein A and peptide affinity chromatography. View in English? Yan, Y. This antibody also cross-reacts with unidentified proteins of 32 kDa, 80 kDa and kDa. KEGG i.

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View Article. Customer shall not use any Product for any diagnostic or therapeutic purpose, or otherwise in any manner that conflicts with its labeling statement. Image Gallery Learn more about how we get our images.

The term 'domain' is atg14 molecular weight here in its wide acceptation, it may be a structural domain, a transmembrane region or a functional domain. CCDS i. PathwayCommons i. RNAct i. This is known as the 'taxonomic identifier' or 'taxid'.

Pfam protein domain database More NOTE : Volumes are for 10 cm atg14 molecular weight 10 cm cm 2 of membrane; for different sized membranes, adjust volumes accordingly. No regulation data available. Click "Literature Details" to view all literature information for this locus, including shared literature between genes.

Description

Do not aliquot the antibody. PaxDb, a database of protein abundance averages across all three domains of life More Pfam protein domain database More Click "Phenotype Details" to view all phenotype annotations and evidence for this locus as well as phenotypes it shares with other genes. ComplexPortal i.

VEuPathDB i. Genevisible i. OrthoDB i. Forms homooligomers; homo-oligomerization is essential for the roles in membrane tethering and enhancement of SNARE-mediated fusion By similarity.

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Fungal Protein Annotation Program. Certificate of Origin. Wash three times for 5 min each with 15 ml of TBST. Sun, Q. Pore size 0. NONH for all modes of transport.

Database of interacting proteins More Beclin 1 Rabbit Polyclonal antibody AP. Itakura, E. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence s displayed. Flash Point F Not applicable. Basic sequence-derived length, molecular weight, isoelectric point and experimentally-determined median abundance, median absolute deviation protein information. Click "Expression Details" to view all expression annotations and details for this locus, including a visualization of genes that share a similar expression pattern.

Powered By OneLink. Integrated resource of protein families, domains and bmi for women sites More OMA i. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary citable accession number'. Aliquoting is unnecessary for o C storage.

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MINT i. Your basket is currently empty. Phosphorylation of phosphatidylinositol PtdIns by a PtdIns 3-kinase is an essential process in autophagy. Products sold or licensed by CST are provided for Customer as the end-user and solely for research and development uses.

Atg14L 1 Publication Manual assertion based on opinion in i Ref. RNAct i. The algorithm is described in the ISO standard. Peer Reviewed Papers. Your basket is currently empty. Atg a key player in orchestrating autophagy. Cell Biol.

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PRIDE i. ProteomicsDB i. PeptideAtlas i. ChiTaRS i. Anti-Atg14 antibody produced in rabbit.

Customer shall a not sell, license, loan, donate or otherwise transfer or make available any Product to any third party, whether alone or in combination with other materials, or use the Products to manufacture any commercial products, b not copy, modify, reverse engineer, decompile, disassemble or otherwise attempt to discover the underlying structure or technology of the Products, or use the Products for the purpose of developing any products or services that would compete with CST's products or services, c not alter or remove from the Products any trademarks, trade names, logos, patent or copyright notices or markings, d use the Products solely in accordance with CST's Product Terms of Sale and any applicable documentation, and e comply with any license, terms of service or similar agreement with respect to any third party products or services used by Customer in connection with the Products. Products are labeled with For Research Use Only or a similar labeling statement and have not been approved, cleared, or licensed by the FDA or other regulatory foreign or domestic entity, for any purpose. Click "Expression Details" to view all expression annotations and details for this locus, including a visualization of genes that share a similar expression pattern. PaxDb i. IgG fraction of antiserum, buffered aqueous solution. Ensembl fungal genome annotation project More

Description

Annotation atg14 molecular weight. The term 'domain' is intended here in its wide acceptation, it may be a structural domain, a transmembrane region or a functional domain. Click "Gene Ontology Details" to view all GO information and evidence for this locus as well as biological processes it shares with other genes.

  • MaxQB i.

  • Liang, C. MilliporeSigma Research.

  • Human Unidentified Gene-Encoded large proteins database More

  • This antibody also cross-reacts with unidentified proteins of 32 kDa, 80 kDa and kDa. Species Reactivity: Human, Mouse.

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Cytosolic under nutrient-rich conditions. Angiotensin II suppresses autophagy and disrupts ultrastructural morphology and function of mitochondria in mouse skeletal muscle. Genevisible i. TreeFam database of animal gene trees More ModBase i Search Bgee i.

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Proceed with detection Weeight D. Aspirate media from cultures; wash cells with 1X PBS; aspirate. Background Autophagy is a catabolic process for the autophagosomic-lysosomal degradation of bulk cytoplasmic contents 1,2. Any use of Product for diagnostic, prophylactic or therapeutic purposes, or any purchase of Product for resale alone or as a component or other commercial purpose, requires a separate license from CST. Social Media.

Select a section on the left to see content. GeneCards i. PaxDb i. GeneCards: human genes, protein and diseases More

The term 'domain' is intended here in its wide acceptation, it atg14 molecular weight be a structural domain, a transmembrane region or a functional domain. These proteins are involved in the formation of autophagosomes, cytoplasmic vacuoles that are delivered to lysosomes for degradation. The molecular machinery of autophagy was largely discovered in yeast and is directed by a number of autophagy-related Atg genes. Length a.

Stack, J. MobiDB: a database of protein disorder and molceular annotations More Save This Selection. Integrated resource of protein families, domains and functional weight More Atg14 and Rubicon were identified based on their ability to bind to Beclin-1 and participate in unique complexes with opposing functions Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Your name Your email. PaxDb, a database of protein abundance averages across all three domains of life More WB : IP : 0.

Charlotte Verified Customer From sample preparation to detection, the reagents you need for your Western Blot are now weight one convenient kit: Western Blotting Application Solutions Kit. Would you like to visit your country specific website? Filter: WB. Click "Expression Details" to view all expression annotations and details for this locus, including a visualization of genes that share a similar expression pattern.

GeneRIFs: Gene References Into Functions

NOTE : Volumes are for 10 cm x 10 cm cm 2 of membrane; for different sized membranes, adjust volumes accordingly. Technical Service. Flash Point C Not applicable.

Physical form Solution in 0. TreeFam database of animal gene trees More GeneID i. Bgee i. Beclin 1-associated autophagy-related key regulator. Required for both basal and inducible autophagy.

Manual assertion based on experiment in i. PRO i. CCDS i. ModBase i. Automatic assertion according to sequence analysis i. Pharos i. Cell Biol.

Except as otherwise expressly agreed in a writing signed by a legally authorized representative of CST, the following terms apply to Products provided by CST, its affiliates or its distributors. MilliporeSigma Research. DIP i.

Fungal Protein Annotation Program. According to the litterature ATG14 atg14 molecular weight supposed to have a diffuse or punctae pattern and not this huge accumulation near the nucleus. Systems used to automatically annotate proteins with high accuracy:. Microcentrifuge for 5 min. Safety Information.

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The final 80 residues in the C-terminus define a minimum required region for autophagosome binding called BATS. Manual assertion inferred from sequence similarity to i. PI3KC3-C1 can associate with further regulatory subunits. The N-terminal cysteine repeats are required for proper localization to the endoplasmic reticulum. Cytosolic under nutrient-rich conditions.

Nonfat Dry Milk : Angiotensin II suppresses autophagy and disrupts ultrastructural morphology and function of mitochondria in mouse skeletal muscle. BioGRID i. Saccharomyces boulardii nom. Immediately scrape the cells off the plate and transfer the extract to a microcentrifuge tube. Yan, Y.

Integrated resource of protein families, domains and functional sites More Atg a key player in orchestrating autophagy. CTD i. Gene Information. All Rights Reserved.

Key features and details

Atg14, a specific subunit of one of the PtdIns 3-kinase mooecular, atg14 molecular weight the complex to the probable site of autophagosome formation, thereby, sorting the complex to This is known as the 'taxonomic identifier' or 'taxid'. NOTE : Please refer to primary antibody product webpage for recommended antibody dilution. Rubicon, which localizes to the endosome and lysosome, inhibits Vps34 lipid kinase activity; knockdown of Rubicon enhances autophagy and endocytic trafficking 11,

Genevisible search portal to normalized and curated expression data from Genevestigator More Safety Information. Reason: Erroneous initiation. IgG fraction of antiserum. Genevisible i. Download protocol.

ComplexPortal i. This is version of the entry and version 1 of the sequence. Atg14 molecular weight have selected weihht top cited antibodies from these vendors for you to compare. Corresponds to variant dbSNP:rs Ensembl. MobiDB: a database of protein disorder and mobility annotations More Ensembl eukaryotic genome annotation project More Modulates the hepatic lipid metabolism PubMed:

This is version of the entry and version 1 of the sequence. Background Autophagy is a catabolic process for the autophagosomic-lysosomal degradation of bulk cytoplasmic contents 1,2. Quality Level.

Your name Your email. Human small intestine tissue lysate. Print datasheet. PhylomeDB i. Pathway Commons web resource for biological pathway data More GeneID i.

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PhylomeDB i. This is known as the 'taxonomic identifier' or 'taxid'. DNASU i. The algorithm is described in the ISO standard. PharmGKB i. InParanoid i.

  • Autophagy-related protein like protein 1 Publication Manual assertion based on opinion in i Ref.

  • Not applicable. Immediately scrape the cells off the plate and transfer the extract to a microcentrifuge tube.

  • RefSeq i.

  • Knockdown of Atg14 inhibits starvation-induced autophagy 11, NOTE : Volumes are for 10 cm x 10 cm cm 2 of membrane; for different sized membranes, adjust volumes accordingly.

Mol Psychiatry Sequential atg14 molecular weight of different layers of dystrophic neurites in Alzheimer's brains. View Article. Incubate weigh in 25 ml of blocking buffer for 1 hr at room temperature. Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others. The histogram division at 0. Dilute to 1X with dH 2 O. Physical form Solution in 0.

Powered By OneLink. Protein sequence database of the Protein Atg114 Resource More Sonicate for 10—15 sec atg14 molecular weight complete cell lysis and shear DNA to reduce sample viscosity. Protein Blotting A general protocol for sample preparation. Changing to another country might result in loss of shopping cart. IntAct i. Integrated resource of protein families, domains and functional sites More

MassIVE i. PeptideAtlas More PRO i. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation.

This antibody also atg14 molecular weight with unidentified proteins of 32 kDa, 80 kDa and kDa. If slight turbidity occurs upon prolonged storage, clarify the solution by centrifugation before use. InterPro i. Sonicate for 10—15 sec to complete cell lysis and shear DNA to reduce sample viscosity. Phosphatidylinositol 3-kinase complex, class III, type I.

Recommended name: Autophagy-related protein 14 Alternative name s : Cytoplasm to vacuole targeting protein PaxDb i. Aspirate media from cultures; wash cells with 1X PBS; aspirate. Basket 0.

Protein interaction database and analysis system More Manual assertion based on experiment in i. Open Targets More Working dilution samples should be discarded if not used within 12 hours. GeneID i.

  • TreeFam i. Open Targets More

  • See complete history. Select a section on the left to see content.

  • Following autophagy stimuli, such as starvation or rapamycin induction, predominantly detected in cytoplasmic foci, identified as isolation membranes and autophagosomes.

  • Conjugate Unconjugated. This product is discontinued.

  • ComplexPortal i.

PhylomeDB i. PRIDE i. Chordata Protein Annotation Program. GeneTree i. Database of comparative protein structure models More EPD i.

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See more citations. Citations Links to gene names and curated GO terms are included within the Summary Paragraphs. EMBO J. In addition, annotations are classified as classical genetics or high-throughput e. These proteins are involved in the formation of autophagosomes, cytoplasmic vacuoles that are delivered to lysosomes for degradation.

Your name Your email. Safety Information. DNASU i. PRIDE i. TreeFam database of animal gene trees More

YES NO. Proceed with detection Section D. Manual assertion based on experiment in i.

ProteomicsDB i. MilliporeSigma Research. Ensembl eukaryotic genome annotation project More PhosphoSitePlus i.

YES NO. Validation Data Gallery. In contrast, Atg14 localizes to autophagosomes, isolation membranes and ER, and can enhance Vps34 activity. These annotations have been derived from physical molecular interaction evidence extracted from the literature and cross-referenced in the entry, or by curator inference from information on homologs in closely related species or by inference from scientific background. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first. PRIDE i. Atg14 is present on autophagic isolation membranes and is required for autophagosome formation.

PhosphoSitePlus i. Protein interaction database and analysis system More Anti-Atg14 antibody produced in rabbit.

  • Working dilution samples should be discarded if not used within 12 hours. Peer Reviewed Papers.

  • Pore size 0. Wash three times for 5 min each with 15 ml of TBST.

  • The term 'domain' is intended here in its wide acceptation, it may be a structural domain, a transmembrane region or a functional domain. This is version of the entry and version 1 of the sequence.

  • Reactivity Human, Mouse, Rat.

All manually curated literature for the specified gene, organized into topics according to their relevance to the gene Primary Literature, Additional Literature, atg14 molecular weight Review. Membrane Blocking and Antibody Incubations NOTE : Volumes are for 10 cm x 10 cm cm 2 of membrane; for different sized membranes, adjust volumes accordingly. Customer shall not use any Product for any diagnostic or therapeutic purpose, or otherwise in any manner that conflicts with its labeling statement. Alternative name s :. Protein Blotting A general protocol for sample preparation.

Short name: Barkor 1 Publication Manual assertion based on opinion in i Ref. 11 stone weight bmi for women a multi-organism proteome resource More Protein Sci. Anti-Atg14 antibody produced in rabbit. Several domains are described in this subsection. Working dilution samples should be discarded if not used within 12 hours.

PRIDE i. Pfam protein domain database More Annotation program. Additionally, this section gives relevant information on each alternative protein isoform. Your basket is currently empty.

  • It has been reported that the loss of ATG14 completely blocks autophagic fusion with lysosomes. Ensembl GeneTree More

  • Safety Information. According to the litterature ATG14 is supposed to have a diffuse or punctae pattern and not this huge accumulation near the nucleus.

  • GeneTree i. Protein Ontology More

  • Alternative name s :. At Proteintech, we pride ourselves on our antibody quality, customer service and transparency.

  • Citations These proteins are involved in the formation of autophagosomes, cytoplasmic vacuoles that are delivered to lysosomes for degradation.

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Sun, Q. Belongs to the ATG14 family. Do not aliquot the antibody. PRIDE i. Would you like to visit your country specific website? Flash Point C Not applicable.

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Do not show this banner again. Phosphothreonine Combined sources Manual assertion inferred from combination of experimental and weight evidence i Ref. TCDB i. Systems used to automatically annotate proteins with high accuracy:. Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. Cytosolic under nutrient-rich conditions. HUGE i.

Autophagy, 5 4 atg14 molecular weight, Whenever possible, allele information and additional details are provided. Keep on ice. PRO i. Image Gallery Learn more about how we get our images. Click "Expression Details" to view all expression annotations and details for this locus, including a visualization of genes that share a similar expression pattern. See complete history.

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