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Cretinism is caused by hypothyroidism causes – Cretinism causes

The common cause is iodine deficiency.

Matthew Cox
Tuesday, October 27, 2020
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  • Register for free and gain unlimited access to:. Text with 14 chapters of every aspect of thyroid disease and the associated cutaneous manifesations.

  • It also affects mental growth.

  • Iodine deficiency causes gradual enlargement of the thyroid gland, referred to as a goiter. Other Diagnostic Studies.

  • For example, it may be found on the side of the neck or under the tongue. It is also used to treat thyroid cancer along with surgery and other medicines.

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Hyppothyroidism defects. Laboratory Findings. Infants with untreated hypothyroidism present at birth are at risk of serious problems with both physical and mental development. Description Congenital hypothyroidism is a partial or complete loss of function of the thyroid gland hypothyroidism that affects infants from birth congenital. Categories : Pejorative terms for people Congenital disorders Thyroid disease Endocrine-related cutaneous conditions.

Another method to diagnose primary hypothyroidism is to measure thyroid-stimulating hormone TSH and free thyroxine T4. A child who is suspected to have cretinism requires early diagnosis and treatment. Cretinism: Congenital b underactivity of the thyroid gland at birthwhich results in growth retardation, developmental delay, and other abnormal features. Hormones produced by the thyroid gland — triiodothyronine T3 and thyroxine T4 — have an enormous impact on your health, affecting all aspects of your metabolism. Trends Endocrinol. Thus, the following blood tests are suggested: Free triiodothyronine fT3 Free thyroxine fT4 Total T3 Total T4 Early hypothyroidism is often asymptomatic and can have very mild symptoms.

It is a condition which arises from insufficient production of thyroid hormones by the thyroid gland. Key difference cretknism Hypothyroidism is a condition which arises from insufficient production of thyroid hormones by the thyroid gland. Mental deterioration is common. Hypothyroidism and joint pain? This question is for testing whether or not you are a human visitor and to prevent automated spam submissions.

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They may also have:. There are also a few uncommon symptoms of which can be characterized by appearance, such as yellow skin, puffy cretinism is caused by hypothyroidism causes, hands and feet, enlarged tongue. When maternal iodine levels are insufficient, there is less production of thyroid hormones. Its signs and symptoms include intense cold intolerance and drowsiness followed by profound lethargy and unconsciousness. If this condition is not treated in time, it may result in severe stunted mental and physical growth of a baby.

  • Paediatr Drugs.

  • And over time, the dose you need may change.

  • Int J Health Sci.

  • Soy: Does it worsen hypothyroidism?

  • These cases are classified as central or pituitary hypothyroidism. If untreated, congenital hypothyroidism can lead to intellectual disability and slow growth.

Less commonly, reduction or absence of thyroid hormone production is caused by impaired stimulation of the production process which is normally done by a structure at the base of the brain called the pituitary glandeven though the process itself is unimpaired. Accessed Oct. However, this disease was less mentioned in medical books because it was erroneously considered to be an aesthetic rather than a clinical disorder. PLoS One. Hypothyroidism may not cause noticeable symptoms in the early stages.

The symptoms after the disease include; dry, puffy skin and thinning of the outer third of the eyebrow. In developed countries, thyroid function testing of newborns has assured that in those affected, treatment with the thyroid hormone thyroxine is begun promptly. International Journal of Anthropology. It can be associated with a number of symptoms. In women, ovulation is impeded and infertility is common.

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Show references AskMayoExpert. Cognitive impairment may also range from mild to so severe that the person becomes nonverbal and is dependent on others for basic care. This test helps detect the disorder so as to prevent complications such as mental retardation, physical disabilities, or even death of the newborn. The etymology of cretin is uncertain. It also causes gradual enlargement of the thyroid gland, referred to as goiter.

Cretinism is caused by hypothyroidism causes adequate iodine by a pregnant mother could also help in preventing cretinism occurring in infants. Retrieved Usually, in normal situations, thyroid gland is found at the center of the neck in front, particularly close to the top side of the windpipe. Periodic and genetic cretinisms result from abnormal development or the function of the foetal thyroid gland. The signs and symptoms of hypothyroidism vary, depending on the severity of the hormone deficiency. Authority control. When newborns do have problems with hypothyroidism, the problems may include:.

InKing Carlo Alberto of Sardinia commissioned the first epidemiological study of congenital iodine deficiency syndrome, in northern Savoy where it was frequent. Leave a Reply Cancel reply Your email address will not be published. Autoimmune disorders occur when your immune system produces antibodies that attack your own tissues. Whenever there are abnormalities like these occurring in a newborn, the result is less production of thyroid hormone or no hormone at all. It can also be caused by lithium-based mood stabilizers. More Information Hypothyroidism symptoms: Can hypothyroidism cause eye problems? The point to mention here is that this defect does come about as a result of inherited genes.

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Treatment It can be eliminated by including proper amount of iodine in the diet. Although hypothyroidism most often affects middle-aged and older women, anyone can develop the condition, including infants. For infants, the T4 tablets are generally crushed and mixed with breast milk, formula milk or water.

While the exact cause of cretinism is not known, it is thought that genetic mutation is responsible for the disorder. They lose the sense of taste and smell. In order to understand how this condition manifests, it is paramount to look at how the thyroid gland functions. The Lancet. The newborns may also receive soy-based formulas as well as iron medication.

There are public health campaigns in many countries which involve iodine administration. Namespaces Article Talk. L-thyroxine replacement at starting dose of 1. Typically there is no new collagen deposition. By using our services, you agree to our use of cookies. Powerpoint slides.

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Other signs may include thickened skin, enlarged tongue, or a protruding abdomen. A goiter is the most specific clinical marker of either the direct or indirect insufficient intake of iodine in the human body. Iodine supplements may be recommended to help in preventing damage of the brain. The early 20th century saw the discovery of the relationships of periodic cretinism with hereditary hypothyroidism and of common cretinism with hypothyroidism due to iodine deficiency. Synthroid is the prescribed pill by doctors.

This rare, life-threatening condition is the result of long-term, undiagnosed hypothyroidism. Disorder It is a deficiency disorder. Cretinism can lead to complications such as permanently diminutive physical development, abnormally enlarged thyroid gland- a condition known as goiter, and impaired mental abilities. Blood tests are conducted occasionally to find out the level of the thyroid hormone.

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Mayo Clinic does not endorse companies or products. It results when the hypothalamus fails to produce sufficient thyrotropin releasing hormone TRH. They are as follows: Primary Hypothyroidism — It originates at the cretinisk gland. This medicine helps improve symptoms of thyroid deficiency such as slow speech, lack of energy, weight gain, hair loss, dry skin and cold feeling. A test to help detect if there is presence of genetic and metabolic disorders is ordered by a doctor. Symptoms may include goiterpoor length growth in infants, reduced adult stature, thickened skin, hair loss, enlarged tongue, a protruding abdomen; delayed bone maturation and puberty in children; and mental deterioration, neurological impairment, impeded ovulationand infertility in adults.

The most common cause of hypothyroidism causes an autoimmune disorder known as Hashimoto's thyroiditis. And over time, the dose you need may change. Usually, in normal situations, thyroid gland is found at the center of the neck in front, particularly close to the top side of the windpipe. Some of the conditions that could result in cretinism due hypothalamic related causes are such as congenital defects, ischemic damage, and presence of tumors.

Initially, it's important to make sure you're receiving the correct dose of medicine. Thyroid gland Open pop-up dialog box Close. Cookies help us deliver our services. NICE Guidance. Differentiating Cretinism from other Diseases. Genetics Home Reference has merged with MedlinePlus.

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Microsoft Academic. The appearance may be sallow because of a carotenemia. See your doctor if you're feeling tired for no reason or have any of the other signs or symptoms of hypothyroidism, such as dry skin, a pale, puffy face, constipation or a hoarse voice.

It can also occur in coastal regions, where iodine might have been removed from the soil by glaciation, cretinsim well as leaching by snow, water and heavy rainfall. Women undergo infertility and menstrual irregularities. The person may have goiter. Some earlier symptoms include thin and brittle fingernails, dry and itchy skin, weight gain, water retention and hair loss. More Information Hypothyroidism symptoms: Can hypothyroidism cause eye problems?

  • It has been increasingly recognized that infantile hemangiomas may also lead to consumptive hypothyroidism with the same issues noted above and should be screened for in infants with any large or multiple hemangiomas.

  • The X-rays are performed on the legs of the baby to view the ends of the bone at the joints of the knee.

  • This consumptive hypothyroidism is likely due to overexpression of type 3 deiodinase in the endothelium of vascular tumor.

  • Wikimedia Commons has media related to Congenital iodine deficiency syndrome.

There may be an increased risk cretiinism purpura due to increased mucin and decreased clotting factors. Cretinism may be caused by other causes like antithyroid medications and iodine deficiency. This chapter specifically deals with hypothyroidism and its cutaneous manifestations. Philadelphia, PA: Sauders Elsevier. US National Guidelines Clearinghouse. Both have been largely eliminated in the developed world. In past centuries, the well reported social diseases prevalent among the poorer social classes and farmers, caused by dietary and agricultural monocultures, were: pellagraricketsberiberiscurvy in long-term sailors, and the endemic goiter caused by iodine deficiency.

The Atlantic Monthly. Adult cretinism is caused by hypothyroidism causes without treatment ranges hypothyroidis, to cm 3 ft 3 in to 5 ft 3 independing on severity, sex, and other genetic factors. Initially, babies born without a thyroid gland or with a gland that doesn't work properly may have few signs and symptoms. Neurological impairment may be mild, with reduced muscle tone and coordination, or so severe that the person cannot stand or walk. J Endocrinol Invest. Epidemiology and Demographics. Show more related content.

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More mildly affected areas of Europe and North America in the 19th century were referred to as "goitre belts". The majority of such cases were still socially functional in their pastoral villages. Comment Name Email Website. Synthroid is the prescribed pill by doctors. Medical condition.

Vaused dyshormonogenesis results from mutations in one of several genes involved in the production of thyroid hormones. Open Next post in Dermatology Close. Genetic causes account for about 15 to 20 percent of cases of congenital hypothyroidism. All rights reserved. What is the Cause of the Disease? Cretinism may be caused by congenital causes like thyroid dysgenesis and ectopic thyroid gland.

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The degree of iodine deficiency was milder and manifested primarily as thyroid enlargement rather than severe mental ls physical impairment. Accurate thyroid function tests are available to diagnose hypothyroidism. Retrieved Categories : CS1 maint: Explicit use of et al. When inherited, the condition usually has an autosomal recessive inheritance pattern, which means both copies of the gene in each cell have mutations. Antibodies Antithyroid medications Autoimmune diseases Ectopic thyroid gland Iodine deficiency Infection Inflammation Maternal hypothyroidism Structural changes Thyroid dysgenesis Thyroid dyshormonogenesis Trauma.

When you talk js organificaiton, it is the process that is required to necessitate the synthesis of thyroid hormone. New York, N. Autoimmune disease. As the variety of food sources dramatically increased in Europe and North America and the populations became less completely dependent on locally grown food, the prevalence of endemic goitre diminished.

All patients with suspected hypothyroidism should have a screening TSH and if abnormal referred to caused hypothyroidism endocrinologist or internist. If you have signs or symptoms of myxedema, you need immediate emergency medical treatment. As the variety of food sources dramatically increased in Europe and North America and the populations became less completely dependent on locally grown food, the prevalence of endemic goitre diminished.

It is a state in which the thyroid gland does not produce enough of the thyroid hormones, Thyroxine T4 and Tri-iodothyronine T3. Iodine is an essential element, necessary and primary for the synthesis of thyroid hormones. During pregnancy, there is a substantial increase in the need of thyroid hormones by the body and a substantial risk of hypothyroidism. Congenital iodine deficiency syndrome was especially common in areas of southern Europe around the Alps and was often described by ancient Roman writers and depicted by artists. According to the Oxford English Dictionarythe translation of the French term into "human creature" implies that the label "Christian" is a reminder of the humanity of the afflicted, in contrast to brute beasts. According to Wikipedia, iodine deficiency is often considered as the most common cause of hypothyroidism, but it can also be caused by many other factors.

  • If the medication is mixed with formulas containing iron or soya products, larger doses may be required, as these substances may alter the absorption of thyroid hormone from the gut. Close more info about Hypothyroidism cretinism.

  • Comparison between Cretinism and Hypothyroidism: Cretinism Hypothyroidism Definition It is a condition arising from the deficiency of thyroid hormone, which causes dwarfism and mental retardation.

  • Soy: Does it worsen hypothyroidism?

  • Ultrasound evaluation in particular is helpful in delineating how large the hemangiomas may be and to monitor treatments. Other cutaneous signs of hypothyroidism include dry skin, thin hair and nails.

  • The number of severely affected persons was always a minority, and most persons were only affected to the extent of having a goitre and some degree of reduced cognition and growth.

If you're receiving hormone therapy for hypothyroidism, schedule follow-up visits as often as cretibism doctor recommends. High fiber diets and soy products can alter absorption. Thyroid gland Your thyroid gland is located at the base of your neck, just below the Adam's apple. Thyroxine must be dosed as tablets only, even to newborns, as the liquid oral suspensions and compounded forms cannot be depended on for reliable dosing. NICE Guidance.

The X-rays are performed on the legs of the baby to view the ends of the bone at cretinism is caused by hypothyroidism causes joints of the knee. Also, exposure to radioactive iodine can stimulate a state of hypothyroidism and this method is used to medically treat hyperthyroidism. Initially, it's important to make sure you're receiving the correct dose of medicine. In Switzerland, for example, where soil does not contain a large amount of iodine, cases of congenital iodine deficiency syndrome were very abundant and even considered genetically caused. Thoughts and reflexes are slower. While it is not known why this kind of birth defect occurs, the thyroid may be seen in a different location.

Retrieved 23 December Related Coconut oil: Can it cure hypothyroidism? Hypothyroidism: Can calcium supplements interfere with treatment? PMID The early 20th century saw the discovery of the relationships of periodic cretinism with hereditary hypothyroidism and of common cretinism with hypothyroidism due to iodine deficiency.

Iz is a condition arising from the deficiency of thyroid hypothyroidism causes, which causes dwarfism and mental retardation. Whenever there are abnormalities like these occurring in a newborn, the result is less production of thyroid hormone or no hormone at all. S2CID Mayo Clinic Marketplace Check out these best-sellers and special offers on books and newsletters from Mayo Clinic. In general, children and teens who develop hypothyroidism have the same signs and symptoms as adults do, but they may also experience:. Congenital iodine deficiency has been almost completely eliminated in developed countries through iodine supplementation of food and by newborn screening utilizing a blood test for thyroid function. The person may have goiter.

The aim of this imaging procedure is to distinguish if the condition is being caused by organification defects or congenital absence. The X-rays are performed on the legs of the baby to view the ends of the bone at the joints of the knee. Measurement of the thyroid-stimulating hormone TSH and free thyroxine T4. Among the signs and symptoms of this condition are:.

Although iodine is found in many foods, it is not universally adequately present in all soils. A thyroid scan or technetium is cretinism is caused by hypothyroidism causes by a doctor to help determine if there are any structural abnormalities involving the thyroid gland. If left untreated, it can result into mild to severe impairment of physical and mental growth and development. Retrieved 11 December Secondary Hypothyroidism — It originates at the pituitary gland.

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Hypothyroidism diet Hypothyroidism symptoms: Can hypothyroidism cause eye problems? ISBN Another method to diagnose primary hypothyroidism is to measure thyroid-stimulating hormone TSH and free thyroxine T4.

Congenital hypothyroidism. In developed countries, thyroid function testing of newborns has assured that in those affected, treatment with the thyroid hormone thyroxine is begun promptly. The resulting shortage of thyroid hormones disrupts normal growth, brain development, and metabolism, leading to the features of congenital hypothyroidism. Retrieved 5 October

This test helps yypothyroidism the disorder so as to prevent complications such as mental retardation, physical disabilities, or even death of cretinism is caused by hypothyroidism causes newborn. The most common cause of hypothyroidism is an autoimmune disorder known as Hashimoto's thyroiditis. From Wikipedia, the free encyclopedia. It is a condition arising from the deficiency of thyroid hormone, which causes dwarfism and mental retardation. These levels can be affected by other diseases. The most common forms include Hashimoto's thyroiditis and radioiodine therapy for hyperthyroidism. In adults, ovulation is impeded and infertility is common.

People suffering from this disease cretiniwm depression and have rapid thoughts. When your thyroid doesn't produce enough hormones, the balance of chemical reactions in your body can be upset. The degree of iodine deficiency was milder and manifested primarily as thyroid enlargement rather than severe mental and physical impairment. The term spread more widely in popular English as a markedly derogatory term for a person who behaves stupidly. A majority of babies having cretinism will have their thyroid either underdeveloped or absent.

Archived from the original on It is a condition arising from the deficiency of thyroid hormone, which causes causee and mental retardation. Goitermental impairmentpoor growthinfertilityhair loss. Or you may simply attribute them to getting older. It can also be caused by lithium-based mood stabilizers, a medication usually used to treat bipolar disorder.

  • There are public health campaigns in many countries which involve iodine administration. This consumptive hypothyroidism is likely due to overexpression of type 3 deiodinase in the endothelium of vascular tumor.

  • Retrieved

  • It may have the appearance of edema as you would see in venous stasis disease, but will not pit upon pressure.

  • Several hypotheses exist.

Disease and Its Causes. In the United States and many other countries, all hospitals test newborns for congenital hypothyroidism. Merck Manual Professional Version. History and Symptoms. Analysis of vitiligo patients and thyroid dysfunction; 15 of patients 5.

Also, exposure to radioactive iodine can stimulate a state of hypothyroidism and this method is used to medically treat hyperthyroidism. Hypothyroidism: Should I take iodine supplements? Synthroid is a pill used to counteract to generic Levothyroxine. Iodine deficiency causes gradual enlargement of the thyroid gland, referred to as a goiter. For other uses, see Cretin.

Please login or register first to view this content. Interestingly, 0 of 50 patients with segmental vitiligo had any thyroid dysfunction. Its signs and symptoms include intense cold intolerance and drowsiness followed by profound lethargy and unconsciousness. For reasons that remain unclear, congenital hypothyroidism affects more than twice as many females as males. There are many different conditions that have been reported to be associated with thyroid disease.

In adults, ovulation is impeded and infertility is common. Cutaneous differences included increased risk for urticaria and puffiness of the hands and feet, yellow to ivory hypothyroidism in patients with typically dark type 4 to 5 skin, and rough dry skin. Medical condition. In past centuries, the well reported social diseases prevalent among the poorer social classes and farmers, caused by dietary and agricultural monocultures, were: pellagraricketsberiberiscurvy in long-term sailors, and the endemic goiter caused by iodine deficiency.

It has affected many people worldwide and continues to be a major public health problem in many countries. It can be so severe that the person cannot stand or walk. Some of the conditions that could result in cretinism due hypothalamic related causes are such as congenital defects, ischemic damage, and presence of tumors. Global Fortification Data Exchange. Pause in the growth of height is apparent in the first year of life. The person may have goiter. It can also occur in coastal regions, where iodine might have been removed from the soil by glaciation, as well as leaching by snow, water and heavy rainfall.

  • Citation on PubMed. Dry skin and pruritus is one of the most common symptoms seen of hypothyroidism but not specific.

  • There is evidence of goiter, and its medical treatment with iodine-rich algae and burnt sponges, in Chinese, Egyptian, and Roman ancient medical texts. Image Courtesy: quizlet.

  • This consumptive hypothyroidism is likely due to overexpression of type 3 deiodinase in the endothelium of vascular tumor.

  • Some earlier symptoms include thin and brittle fingernails, dry and itchy skin, weight gain, water retention and hair loss. According to Wikipedia, iodine deficiency is often considered as the most common cause of hypothyroidism, but it can also be caused by many other factors.

  • There is evidence of goiter, and its medical treatment with iodine-rich algae and burnt sponges, in Chinese, Egyptian, and Roman ancient medical texts. At first, you may barely notice the symptoms of hypothyroidism, such as fatigue and weight gain.

  • The majority of such cases were still socially functional in their pastoral villages. Please login or register first to view this content.

If dietary modification occurs one may want to check thyroid levels more regularly than every year. Namespaces Home Page Discussion. At first, you may barely notice the symptoms of hypothyroidism, such as fatigue and weight gain. When hypothyroidism in infants isn't treated, even mild cases can lead to severe physical and mental retardation.

As the disease progresses, infants are likely to causes trouble feeding and may fail to grow and develop normally. Mayo Clinic does not endorse companies or products. Cretiniam have slow speech and hoarse voices. Tertiary Hypothyroidism — It originates at the hypothalamus. Although iodine is found in many foods, it is not universally adequately present in all soils. It has affected many people worldwide and continues to be a major public health problem in many countries. The most common cause of hypothyroidism is an autoimmune disorder known as Hashimoto's thyroiditis.

Directions to Hospitals Treating Cretinism. The etymology of cretin is uncertain. CS1 maint: Explicit use of et al.

Other drugs that may cause hypothyroidism include amiodarone, interferon alpha, interleukin-2 and thalidomide. A thyroid scan or technetium is ordered by a doctor to help determine if there are any structural abnormalities involving the thyroid gland. S2CID Neurological impairment may be mild with reduced muscle tone and coordination.

For cretinsm that remain unclear, congenital hypothyroidism affects more than twice as many females as males. If treatment begins in the first two weeks after birth, infants usually develop normally. Your thyroid is a small, butterfly-shaped gland situated at the base of the front of your neck, just below your Adam's apple. There are many different conditions that have been reported to be associated with thyroid disease.

In general, children and teens who develop hypothyroidism have the same signs and symptoms as adults cretibism, but they may also experience:. Hypothyroidism may be due to a number of factors, including:. Having adequate iodine by a pregnant mother could also help in preventing cretinism occurring in infants. In: Harrison's Principles of Internal Medicine. Hypothyroidism underactive thyroid is a condition in which your thyroid gland doesn't produce enough of certain crucial hormones.

Both have been largely eliminated in the developed world. When hypothyroidism in infants isn't treated, even mild cases can lead to severe physical and mental retardation. It can also be related to increased stress. Cretinism is a condition arising from the deficiency of thyroid hormone, which causes dwarfism and mental retardation. A myxedema coma may be triggered by sedatives, infection or other stress on your body. Leave a Reply Cancel reply Your email address will not be published. In women, ovulation is impeded and infertility is common.

Case control study looking at consultation comparing hypothyroid and euthyroid. The earliest Alpine hypotyhroidism climbers sometimes came upon whole villages affected by it. Int J Health Sci. When newborns do have problems with hypothyroidism, the problems may include:. Learn more. Because of its pejorative connotations in popular speech, health-care workers have mostly abandoned the term "cretin".

Secondary Hypothyroidism — It originates at the pituitary gland. This rare, life-threatening condition is the result of long-term, undiagnosed hypothyroidism. It also affects mental growth.

As the variety of food sources dramatically increased in Europe and North America and the populations cretinism is caused by hypothyroidism causes less completely dependent on locally grown food, the prevalence of endemic goitre diminished. It can be so severe that the person cannot stand or walk. It can also occur in coastal regions, where iodine might have been removed from the soil by glaciation, as well as leaching by snow, water and heavy rainfall. Pause in the growth of height is apparent in the first year of life. Cretinism can lead to complications such as permanently diminutive physical development, abnormally enlarged thyroid gland- a condition known as goiter, and impaired mental abilities.

Hypothyroidism diet Hypothyroidism symptoms: Can hypothyroidism cause eye problems? If you have signs or symptoms of myxedema, you need immediate hypothgroidism medical treatment. There is caused hypothyroidism the option of taking T4 individually, as it is the standard form; or taking T4 and T3 in combination. Cretinism is a condition arising from the deficiency of thyroid hormone, which causes dwarfism and mental retardation. It also causes gradual enlargement of the thyroid gland, referred to as goiter. Chaker L, et al.

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