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C57bl 6 mice obesity in america: Persistent diet-induced obesity in male C57BL/6 mice resulting from temporary obesigenic diets

References 1.

Matthew Cox
Sunday, February 21, 2021
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  • Nutrients ; 4 : — Wu et al.

  • Cardiac fibrosis was assessed from picrosirius red staining of left ventricles.

  • References U. ChristiansKendra I.

  • Ursolic acid derivatives for pharmaceutical use: a patent review Understanding disease etiopathogenesis is crucial for the development of new therapeutic interventions, but human environmental influence on disease ontogeny cannot be recreated in a laboratory setting nor can they exert the same effect on another species.

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Download references. Al-Daghri, M. When BMD was expressed relative to body weight, differences due to diet were observed suggesting that the obsity density did not increase relative to the increase in body weight Table 3. At the end of the 12 weeks study period, although the HFD treated mice had maximum weight gain, there was no effective weight loss with orlistat and EMfC treatments also.

  • Fedke et al. Increased level of the circulating free fatty acids also leads to macrophage activation and the production of proinflammatory cytokines via Toll-like receptors TLRs [ 3 ].

  • Reprints and Permissions. We assessed smooth muscle contractility, endothelial-dependent and -independent relaxation, and penile neurotransmitter-mediated relaxation.

  • Halade, M. Belalcazar, C.

  • Droke, K. According to the US National Cancer Institute, human foods and beverages can be divided into 97 categories, such as grain-based desserts, pasta and pasta dishes, beef and beef-mixed dishes and so on, with many subcategories.

  • Al-Attas et al.

  • The rising prevalence of CVD in premenopausal women may be attributed to an increased prevalence of women entering pregnancy with an overweight or obese BMI. Mouse model of erectile dysfunction due to diet-induced diabetes mellitus.

Molecular Pharmaceutics5 2 Diabetes ; 57 : — Total RNA molecules were isolated by centrifugation at 15, rpm for 15 min, after which the concentration was measured by UV spectroscopy. Lerner et al. Citations are the number of other articles citing this article, calculated by Crossref and updated daily.

Received : 24 February Calhau, and I. Critical Reviews in Food Science and Nutrition59 20 Acta Diabetol ; 50 : — Phytochemistry Reviews20 1 Journal of Functional Foods69 ,

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Importance of different grades of abdominal obesity on testosterone level, erectile dysfunction, and clinical coincidence. Likewise, HFD did not impair penile neurotransmitter-mediated relaxation. Cite this article Odom, M. Current mouse models of high-fat diet HFD -induced obesity yield conflicting results. Article Google Scholar.

  • In the absence of amreica in tibia trabecular and cortical bone microarchitecture, it is conceivable that the absence of alterations in the tibia could result from site-specific changes associated with increased adiposity and greater weight-bearing, which could offset some of the negative effects of glucose intolerance on bone [ 4849 ]. Kuhn, C.

  • Obesity and the pubertal transition in girls and boys.

  • Considering the duration of study, Sone and Kagawa 46 conducted their study for 1 year, which is the same as Winzell and Ahren. Plant triterpenoid saponins: biosynthesis, in vitro production, and pharmacological relevance.

  • Abstract Susceptibility to obesity changes during the course of life.

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  • Liu, and K. Murphy, K.

Mouse maerica of erectile dysfunction due to diet-induced diabetes causes of child obesity articles for children. Prevalence of cardiovascular risk factors in erectile dysfunction. Long term high fat diet treatment: an appropriate approach to study the sex-specificity of the autonomic and cardiovascular responses to obesity in mice. Rent or Buy article Get time limited or full article access on ReadCube. Publication types Research Support, N. All serum hormones and metabolites returned to control levels with the exception of a trend for increased leptin.

In: Matthew Wright. For example, the type of protein may modulate weight gain in rodents—rats fed soy diets have less hepatic lipid deposition, no hyperleptinemia and less overall weight than those fed casein diets. Chia-Jung Wu and Chia-Wei Lin were involved in the acquisition of histological morphology and protein expression. In addition to the effect of dietary modification, primary and secondary effects of the genetic manipulation itself may heavily influence the observed phenotype. ZaccariaF. Svenson, R. Fasting of mice: a review.

  • Articles from Experimental and Therapeutic Medicine are provided here courtesy of Spandidos Publications. Feskanich, W.

  • We used microarray analysis of gene expression during development of inguinal fat to show that molecular networks of lipogenesis were maximally expressed at 8 weeks-of-age.

  • Journal of Berry Research10 3 ,

  • Tsukumo, M. Cell Metab ; 1 : —

Kuruvilla, S. CiarapicaM. Figure 5. Murphy, K. In order for a rodent model to have relevance to human disease, it should effectively recapitulate the natural history, pathophysiology and complications in a manner similar to what is observed in humans. Diabetes ; 55 : —

Cox, and F. Fajardo, L. Bioactive metabolites from macrofungi: Ethnopharmacology, biological activities and chemistry. Durlach, G.

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Activation of the ghrelin receptor also results in an inhibition of proinflammatory cytokine expression and an increase in survival in various inflammatory disease models [ 3132 ]. The extracts were dissolved in DMSO cat. RobertsKaliopi ChrysovergisPaul A. Gao, D.

PalombaAmericx. Skip to main content Thank you for visiting nature. Gnilka et al. Journal of Agricultural and Food Chemistry60 23 Trends in carbohydrate, fat, and protein intakes and association with energy intake in normal-weight, overweight, and obese individuals: Physiol Behav ; 89 : — Several reports have shown that a high fat diet uncouples bone turnover by increasing bone resorption and decreasing bone formation in various rodent models [ 161721 ].

  • Measurement of fat weight and adipocyte size. There are many other examples of highly disparate results arising from the combination of HFD feeding with genetic modification.

  • View author publications. Skip to main content Thank you for visiting nature.

  • Considerations in the design of hyperinsulinemic-euglycemic clamps in the conscious mouse. European Food Research and Technology10 ,

  • Interestingly, endothelial-dependent and -independent relaxation was unchanged in both systemic and penile vasculature. Article Google Scholar 9.

Zhao, and E. Age, weight and obesity. Liu, and K. Molecules25 8 ,

Al-Daghri, M. Targets and mechanisms of dietary anthocyanins to combat hyperglycemia and hyperuricemia: a comprehensive review. The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Arda Ozturkcan. Of rodents and men: species-specific glucose regulation and type 2 diabetes research.

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Surwit, C. Abstract Type 2 diabetes mellitus T2DM represents a complex clinical scenario of altered energy metabolism and increased fracture incidence. Protoplasma6 Mensink et al.

J Sex Med. Treatment with metformin improves erectile dysfunction in a murine model of ovesity associated with insulin resistance. Ethics declarations Conflict of interest America authors declare no competing interests. Trends in obesity among adults in the United States, to Bigger is not always better: the effect of obesity on sexual satisfaction and behavior of adult men in the United States. J Diabetes Res. An overview of murine high fat diet as a model for type 2 diabetes mellitus.

Conclusions: These results suggest that the combined effects of pregnancy and obesity augment cardiac hypertrophy and promote remodeling. Br J Pharm. However, HFD did not impair pre-penile or penile smooth muscle vasoreactivity as demonstrated in previous studies, suggesting that this preclinical model does not accurately represent the clinical phenotype of obesity-induced ED. Download citation. Plasma leptin, but not adiponectin, concentrations were correlated with LV mass in HF-fed females.

Journal of Nutrition and Metabolism

Weekly food intake, weight gain, and body-fat percentage were measured. Int J Impot Res. Rights and permissions Reprints and Permissions.

In this study, to analyze the un effect of EMfC, we used orlistat as a positive control for assessing the anti-obesity effect in HFD-induced obese mice. Images generated from the scans of the vertebrae were analyzed at a threshold of and a sigma and support of 1. Circulation ; : — The addition of age, sex and strain-dependent HFD feeding atop already complicated chemical T2DM induction renders intra- and inter-species extrapolation impossible. More related articles. The acquired images were analyzed at a threshold ofa sigma of 0.

Science ; : — Murphy, K. Introduction Obesity is associated with insulin resistance and an abnormal inflammatory response [ 12 ]. Received 27 Jul

Table 2. Academic Editor: Luca Cantarini. Representative images were photographed and are presented at a 10x magnification. King AJF. Journal of Functional Foods64 ,

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J Agric Food Chem. Ashcroft, and R. Although this does not obesitg out alterations in bone metabolism occurring earlier, future studies are needed to investigate the mechanism involved in the site-specific loss of bone observed in this animal model. PNU approved the protocol for the present study. Considerations in the design of hyperinsulinemic-euglycemic clamps in the conscious mouse.

Publication types Research Support, N. We sought to determine onesity mechanism activating the fat accumulation in B6 mice at 8-weeks-of-age. Aortas from both strains that fed a HFD had decreased contraction, yet contraction was unchanged in HFD pudendal arteries and penises. To obtain the best experience, we recommend you use a more up to date browser or turn off compatibility mode in Internet Explorer. Article Google Scholar 5.

SilveiraDalgimar B. VMH lesions are generally induced by administration amrrica monosodium glutamate or direct electrical shock to create bilateral destruction of the ventromedial and arcuate hypothalamic nuclei. J Cell Mol Med ; 16 : — Molecules25 12 Deletion of the mouse Slc30a8 gene encoding zinc transporter-8 results in impaired insulin secretion. Similarly, the common mouse strains also range between obesity-prone and obesity-resistant. Cheng-Shyuan Rau provided and coordinated the resources.

Introduction

Access through your institution. Exposure of juvenile rats to the phytoestrogen daidzein impairs erectile function in a dose-related manner in adulthood. You are using a browser version with limited support for CSS.

  • Numerous studies reported that several lipolytic agents, including norepinephrine, isoproterenol, phoscholine, dibutyl-cAMP DBcAMP and theophylline induce lipolysis in adipocytes Full size image.

  • Abstract Background: Over a third of reproductive-age women in the USA are obese, and the prevalence of cardiovascular disease CVD is rising in premenopausal women.

  • Cordycepin stimulated steroidogenesis in MA mouse Leydig tumor cells through the protein kinase C Pathway.

  • Article Google Scholar. From birth to 8 weeks-of-age, both male and female S mice had significantly higher fat mass and adiposity index than B6 mice, although they were not obese.

  • Body weight was increased after 7 weeks on both obesigenic diets Publication types Research Support, N.

Purina TestDiet, Obeisty. Cordycepin stimulated steroidogenesis in MA mouse Leydig tumor cells through the protein kinase C Pathway. Cordycepin prevents hyperlipidemia in hamsters fed a high-fat diet via activation of AMP-activated protein kinase. As shown on Table 2these studies reported age- sex- strain- and diet-dependent phenotypic variability for example, glucose tolerance, insulin secretion, body weight, etc.

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Decreased energy intake and increased energy expenditure, which reduces adiposity and restore insulin sensitivity, are the two most commonly recommended lifestyle changes to treat DIO and its related disorders [ 15 ]. However, as discussed below, the development, severity and duration of these metabolic perturbations are highly variable due to several factors such as the age at which HFD feeding starts, duration of HFD feeding, sex and the rodent species as well as the strain used, 29 rendering data analysis and extrapolation very difficult. Food Research International, J Biol Chem. Gastrointestinal tract plays an important role in DIO and other nutrition-related disorders, as it represents the route by which all nutrients and other sources of energy are ingested, processed, and absorbed [ 50 ].

Reilly, M. Acta Cir Bras ; 21 : — Ledford H. Falch, and S.

Mediators of Inflammation

Critical Reviews in Food Science and Nutrition58 4 Gross et al. Consequently, only a few anti-diabetic drugs are currently available on the market despite the substantial amount of information acquired thus far from animal studies of obesity and diabetes. Journal overview.

Commonly known as mulberry in Korea, Morus alba family: Mulberrygrows in northern China, and has been cultivated from India to the Middle East, southern Europe, and recently North America. Ameliorative effects of mulberry Morus alba L. Riu, T. The extracts were dissolved in DMSO cat. Thus, the results provide evidence for the potential use of EMfC as an anti-obesity complex in the treatment of obesity. Interestingly, the serum analysis of the experimental group including EMfC treatment for 12 weeks showed no adverse side effects such as hepatotoxicity and kidney toxicity data not shown. Looker, K.

Bigger is not always better: the effect of obesity on sexual satisfaction and behavior of adult men in the United States. Search Search articles by subject, keyword or author. Article Google Scholar 8. We assessed smooth muscle contractility, endothelial-dependent and -independent relaxation, and penile neurotransmitter-mediated relaxation. In addition, the DNA methylation analysis of the Sfrp5 promoter and binding of acetylated histones to Sfrp5 and Acly promoter regions showed that major differences in the expression of genes of lipogenesis and chromatin structure occur during development.

Gnilka et al. Accepted 12 May To further elucidate the mechanisms by which EMfC affects obesity, we measured the mRNA levels of several key genes that affecting adipogenesis and lipogenesis in the liver tissue. Nature ; doi MenezesTiago S.

Body weight was increased after 7 weeks on both obesigenic diets Michael R. Br J Pharm. Following delivery, pups were euthanized, and females maintained on respective diets.

  • Deletion of the mouse Slc30a8 gene encoding zinc transporter-8 results in impaired insulin secretion. These mice also showed decreased lipid accumulation in the liver, including a significant decrease in liver triacylglycerol concentration.

  • Am J Mens Health.

  • HagerAaron Hager and Luke R.

  • Received : 15 January

  • This leads to obesity primarily by hyperphagia and lack of control between energy absorption and expenditure governed by leptin, neuropeptide Y and insulin feedback mechanisms.

Cite this article Odom, M. Restoration of perivascular adipose tissue function in diet-induced obese mice without changing bodyweight. Rights and permissions Reprints and Permissions. Revised : 01 April

Bigger is not always better: the effect of obesity on sexual satisfaction and behavior of adult men in the United States. After the switch to chow, the HF-C and EN-C groups lost weight but subsequently maintained a state of persistent obesity in comparison to the C group Article Google Scholar. Rights and permissions Reprints and Permissions.

Shimomura, E. Gnilka et al. Journal of Berry Research10 3 Author information Article notes Copyright and License information Disclaimer. Given the breadth of the literature on this topic, only representative examples are discussed below.

Morphological and functional evidence for the contribution of the pudendal artery in aging-induced erectile dysfunction. Body obesty was increased after 7 weeks on both obesigenic diets In contrast to pregnancy, where transiently increased left ventricular LV mass is not associated with cardiac damage, obesity-mediated cardiac hypertrophy is pathological. Abstract Background: Does diet-induced obesity persist after an obesigenic diet is removed?

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Abstract Susceptibility to obesity changes during the course of life. We used microarray analysis of gene expression during development of inguinal fat to show that molecular networks of lipogenesis were maximally expressed at 8 weeks-of-age. References 1. The rising prevalence of CVD in premenopausal women may be attributed to an increased prevalence of women entering pregnancy with an overweight or obese BMI. Men Masc.

Santos and Vietla S. The study found that genes in both fatty acid metabolism and oxidation showed different regulation patterns between obese human and rats. In the end of the experiment, all mice were euthanized, and the epididymal white adipose tissue WAT of each mouse was collected and weighed. Published 03 Jun

Mulberry leaf extract stimulates glucose uptake and GLUT4 translocation in rat adipocytes. J Nutr ; : — Sartipy and D. Revised : 18 June

Received : 15 January Tax calculation will be finalised during checkout. Heydemann A. After the switch to chow, the HF-C and EN-C groups lost weight but subsequently maintained a state of persistent obesity in comparison to the C group Am J Mens Health.

Expression of adipogenesis and lipogenesis associated genes in liver tissue. VenneriaD. Journal of Agricultural and Food Chemistry59 12 PLoS Biol ; 8 : e Marcelin G, Chua S. At the end of the experiment, the difference in body weight gained between the DIO and control groups reached

  • High-fat diet-induced hyperglycemia and obesity in mice: differential effects of dietary oils.

  • Both strains fed 12 weeks of HFD-developed obese phenotypes.

  • This leads to obesity primarily by hyperphagia and lack of control between energy absorption and expenditure governed by leptin, neuropeptide Y and insulin feedback mechanisms. Cornus mas L.

  • Mouse genomic variation and its effect on phenotypes and gene regulation. Access through your institution.

Gharavi, W. Anti-inflammatory and anti-cancer activity of mulberry Morus alba L. The effect of previous diet on the ability of animals to do work during subsequent fasting: one figure. Reilly, M. Stroh et al. Nat Genet ; 37 : —

Lean ME. Nevertheless, it is important to determine whether HFD data from different laboratories and within the same laboratory can be reliably compared and extrapolated. Choi, Y. Figure 2. In addition, emerging literature has implicated HFD-induced alterations in gut microbiota in the obesity epidemic [ 53 ]. Trends in carbohydrate, fat, and protein intakes and association with energy intake in normal-weight, overweight, and obese individuals:

Cite this article Odom, M. Heydemann A. Odom Authors Michael R.

Lai, M. Fat mobilization in adipose tissue is promoted by adipose triglyceride lipase. Primary factors contributing to the variability observed in HFD-fed rodent models. Dahlberg, U.

In contrast to pregnancy, where transiently increased left ventricular LV ameirca is not associated with cardiac damage, obesity-mediated cardiac hypertrophy is pathological. Access through your institution. Abstract Susceptibility to obesity changes during the course of life. Revised : 01 April Body weight was increased after 7 weeks on both obesigenic diets

Article Google Scholar 8. Article Google Scholar Exposure of juvenile rats to the phytoestrogen daidzein impairs erectile function in a dose-related manner in adulthood. Show results from All journals This journal.

Falany, W. Biochem Biophys Res Commun ; : — More related articles. Lang et al. Nakata, T.

  • Anthocyanin and ursolic acid treated mice exhibited extremely elevated insulin levels. Each group included seven animals.

  • Mouse strain-dependent variation in obesity and glucose homeostasis in response to high-fat feeding. The purpose of this study was to determine the long-term effect of obesity during pregnancy on cardiac function and structure in mice.

  • Elizabeth Rendina-Ruedy, Kelsey D.

  • Mouse strain-dependent variation in obesity and glucose homeostasis in response to high-fat feeding.

  • Interestingly, the serum analysis of the experimental group including EMfC treatment for mce weeks showed no adverse side effects such as hepatotoxicity and kidney toxicity data not shown. As mice continue to be used for models of impaired glucose homeostasis, further investigation is warranted to fully understand these strain differences relative to metabolic handling.

Buy or subscribe. Heydemann A. We assessed smooth muscle contractility, endothelial-dependent and -independent relaxation, and penile neurotransmitter-mediated relaxation. Article Google Scholar 8.

Search Search articles by subject, keyword or author. One of the major risk factors for the development of insulin resistance and subsequent T2DM is obesity, another epidemic affecting 2. Lippiat, P. Functional properties of Cornelian cherry Cornus mas L.

Journal of Ethnopharmacology, Lab Anim Res. Schlauch et al. The VOI was analyzed using a threshold ofa sigma of 0.

Article Google Scholar 3. BJU Int. Cardiac fibrosis was assessed from picrosirius red staining of left ventricles. Trends in obesity among adults in the United States, to

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Mol Pharmacol ; 80 : — Pharmacological management of appetite expression in amdrica. In addition, to study the changes c57bl 6 mice obesity in america body weight as a consequence of changes in dietary intake data not showna slight decrease was observed in dietary intake of the experimental group including the vehicle groupwith no obvious difference between. Abstract Much attention has been focused on food that may be beneficial in preventing diet-induced body fat accumulation and possibly reduce the risk of diabetes and heart disease. Chidsey-Frink, H. Journal of Functional Foods64 ,

Ameriac Background: Causes of child obesity articles for children a third of reproductive-age women in the USA are obese, and the prevalence of cardiovascular disease CVD is rising in premenopausal women. Received : 15 January Mechanisms responsible for obesity-induced ED are unknown. From birth to 8 weeks-of-age, both male and female S mice had significantly higher fat mass and adiposity index than B6 mice, although they were not obese. Odom, Trevor C. J Gend Specif Med. Thank you for visiting nature.

Vis Neurosci ; 22 : — Elizabeth Rendina-Ruedy, Kelsey D. Nutrients9 6 SimonDawn J. Introduction Increasing prevalence of type 2 diabetes mellitus T2DM has stimulated research focused on the pathogenesis and treatment of T2DM and its complications. These mice also showed decreased lipid accumulation in the liver, including a significant decrease in liver triacylglycerol concentration.

Selective breeding for diet-induced obesity and resistance in Sprague-Dawley rats. Nutrition Research36 12 Fluorescence intensity was measured at the end of the extension phase of each cycle. Lucas, Brenda J.

In addition to jice synthesis of TG stored in adipose tissue, lipolysis hydrolysis is an important mechanism for fat accumulation in adipose tissue. Dis Model Mech ; 5 : — If, as we hypothesized, the metabolic response to a HF diet in these two substrains differs due to genetic variations, this may alter the inflammatory response, hormones, and adipokines, subsequently affecting the bone. Silva et al.

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Exposure of juvenile rats to jice phytoestrogen daidzein impairs erectile function in a dose-related manner in adulthood. Restoration of perivascular adipose tissue function in diet-induced obese mice without changing bodyweight. From birth to 8 weeks-of-age, both male and female S mice had significantly higher fat mass and adiposity index than B6 mice, although they were not obese. Recent advances in the treatment of erectile dysfunction. Results: HF-fed postpartum mice had markedly greater weight gain and fat mass expansion with obesity, associated with significantly increased LV mass, cardiac output, and stroke volume compared with HF-fed nulliparous mice.

After 20 weeks of diet feeding, cardiac function was quantified by echocardiography, and plasma smerica and adiponectin concentrations quantified in LF- and HF-fed postpartum and nulliparous females. Mechanisms responsible for obesity-induced ED are unknown. Mouse strain-dependent variation in obesity and glucose homeostasis in response to high-fat feeding. Abstract Background: Does diet-induced obesity persist after an obesigenic diet is removed?

Show results from All journals This journal. Odom, Trevor C. After 20 weeks of diet feeding, cardiac function was quantified by echocardiography, and plasma leptin and adiponectin concentrations quantified in LF- and HF-fed postpartum and nulliparous females. Access through your institution.

Figure mie. Metabolism ; 49 : — McCready, and S. Novel insights in health-promoting properties of sweet cherries. Journal of Agricultural and Food Chemistry57 19 IDF Diabetes Atlas5th edn. The therapeutic effects of mulberry Morus alba leaves on lipid metabolism, including lipogenesis, lipolysis and hyperlipidemia are widely known, although their fermented products are yet to be applied.

This article is cited by publications. Panchal SK, Brown L. Ye and J. Abstract Much attention has been focused on food that may be beneficial in preventing diet-induced body fat accumulation and possibly reduce the risk of diabetes and heart disease. Synergistic action of ursolic acid and metformin in experimental model of insulin resistance and related behavioral alterations. Expression of lipolysis associated proteins in liver tissues. Bauer et al.

Current mouse models of high-fat diet HFD -induced obesity yield conflicting results. All prices are NET prices. Search Search articles by subject, keyword or author. Following delivery, pups were euthanized, and females maintained on respective diets.

Endothelininduced responses in isolated mouse vessels: the expression and function of receptor types. Following delivery, pups were euthanized, and females maintained on respective diets. Article Google Scholar 5. Abstract Obesity can lead to cardiovascular disease, diabetes, and erectile dysfunction EDwhich decreases overall quality of life. After 20 weeks of diet feeding, cardiac function was quantified by echocardiography, and plasma leptin and adiponectin concentrations quantified in LF- and HF-fed postpartum and nulliparous females.

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Correspondence to Johanna L. Body weight was increased after 7 weeks on both obesigenic diets Article Google Scholar 9. Accepted : 13 April Plasma leptin, but not adiponectin, concentrations were correlated with LV mass in HF-fed females. Advanced search.

Int J Impot Res Michael R. Cardiac fibrosis was assessed from picrosirius red staining of left ventricles. Endothelininduced responses in isolated mouse vessels: the expression and function of receptor types. All prices are NET prices.

Commonly known as mulberry in Korea, Morus alba family: Mulberrygrows in c57bl 6 mice obesity in america China, and has been cultivated from India to the Middle East, southern Europe, and recently North America. The therapeutic effects of mulberry Morus alba leaves on lipid metabolism, including lipogenesis, lipolysis and hyperlipidemia are widely known, although their fermented products are yet to be applied. J Nutr Metab ; : VMH lesions are generally induced by administration of monosodium glutamate or direct electrical shock to create bilateral destruction of the ventromedial and arcuate hypothalamic nuclei.

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  • You can also search for this author in PubMed Google Scholar. We used microarray analysis of gene expression during development of inguinal fat to show that molecular networks of lipogenesis were maximally expressed at 8 weeks-of-age.

  • Nature ; : —

  • Long term high fat diet treatment: an appropriate approach to study the sex-specificity of the autonomic and cardiovascular responses to obesity in mice. Substances Adiponectin Leptin.

  • Conclusion: Our results illustrate the importance of considering the history of energy imbalance in determining body weight and that a persistent elevation of body weight after removal of obesigenic diets can result from very small increases of energy intake.

Furthermore, unlike humans, mice consume most of their food at night. Obesity is associated with ni resistance and an abnormal inflammatory response [ 12 ]. Morinda citrifolia Linn. Western-style fast food intake and cardio-metabolic risk in an Eastern country. We therefore suggest that compared to OT, EMfC is likely to be more efficient in contributing to lipolysis. Altex ; 31 : — WBC 1 10 5.

Prevalence of cardiovascular risk factors in erectile dysfunction. BJU Int. Endothelininduced responses in isolated mouse vessels: the expression and function of receptor types. References 1. Access through your institution.

We sought to determine the mechanism activating the fat accumulation in B6 mice at 8-weeks-of-age. Esposito K, Giugliano D. In contrast to pregnancy, where transiently increased left ventricular LV mass is not associated with cardiac damage, obesity-mediated cardiac hypertrophy is pathological.

Results: HF-fed postpartum mice had markedly greater weight gain and fat mass expansion with obesity, associated with significantly increased LV mass, obdsity obesity, and stroke volume compared with HF-fed nulliparous mice. Rent or Buy article Get time limited or full article access on ReadCube. Despite the marked increase in LV mass in HF-fed postpartum mice, mRNA abundance of genes regulating fibrosis and interstitial collagen content was similar between HF-fed nulliparous and postpartum mice. J Sex Med.

Based on recent literature describing the hormone OCN mjce a regulator of systemic energy metabolism [ 52 — 54 ], the role of OCN on both metabolic and skeletal changes induced by HF was investigated. Sipos, and P. Defining high-fat-diet rat models: metabolic and molecular effects of different fat types. SilvaTatyanne L. Experimental Parasitology, Targets and mechanisms of dietary anthocyanins to combat hyperglycemia and hyperuricemia: a comprehensive review.

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